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Francis Peyton Rous

Francis Peyton Rous ForMemRS[1] (/raʊs/) (October 5, 1879 – February 16, 1970) was an American Nobel Prize-winning virologist.

Education and early life[edit]

Rous was born in Woodlawn, Maryland in 1879 and received his B.A. and M.D. from Johns Hopkins University.[2]

Career and research[edit]

Rous was involved in the discovery of the role of viruses in the transmission of certain types of cancer. In 1966 he was awarded aNobel Prize in Physiology or Medicine for his work.
In 1911, as a pathologist he made his seminal observation, that a malignant tumor (specifically, a sarcoma) growing on a domestic chicken could be transferred to another fowl simply by exposing the healthy bird to a cell-free filtrate.[3][4] This finding, that cancer could be transmitted by a virus (now known as the Rous sarcoma virus, a retrovirus), was widely discredited by most of the field's experts at that time. Since he was a relative newcomer, it was several years before anyone even tried to replicate his prescient results. Although clearly some influential researchers were impressed enough to nominate him to the Nobel Committee as early as 1926 (and in many subsequent years, until he finally received the award, 40 years later).

Awards and honors[edit]

In addition to the Nobel Prize, Peyton Rous was elected a Foreign Member of the Royal Society (ForMemRS) in 1940,[1] he won theAlbert Lasker Award for Basic Medical Research in 1958 and the National Medal of Science in 1965.

Personal life[edit]

In his later life he wrote biographies of Simon Flexner[5] and Karl Landsteiner.[6]
His wife Marion died in 1985. His daughter Marni Hodgkin was a children's book editor, and the wife of another Nobel Prize winner, Alan Lloyd Hodgkin.[7]

References[edit]

  1. ^ Jump up to:a b c Andrewes, C. H. (1971). "Francis Peyton Rous. 1879-1970". Biographical Memoirs of Fellows of the Royal Society. 17: 643–662. doi:10.1098/rsbm.1971.0025. ISSN 0080-4606.PMID 11615431.
  2. Jump up^ "Peyton Rous – Biography". Nobelprize.org. Retrieved 6 June 2011.
  3. Jump up^ Rous, Peyton (1910). "A Transmissible Avian Neoplasm (Sarcoma of the Common Fowl)". Journal of Experimental Medicine. 12 (5): 696–705. doi:10.1084/jem.12.5.696. PMC 2124810 Freely accessible. PMID 19867354.
  4. Jump up^ Rous, Peyton (1911). "A Sarcoma of the Fowl Transmissible by an Agent Separable from the Tumor Cells". Journal of Experimental Medicine. 13 (4): 397–411. doi:10.1084/jem.13.4.397.PMC 2124874 Freely accessible. PMID 19867421.
  5. Jump up^ Rous, P. (1949). "Simon Flexner. 1863-1946". Obituary Notices of Fellows of the Royal Society. 6 (18): 408–426. doi:10.1098/rsbm.1949.0006.
  6. Jump up^ Rous, P. (1947). "Karl Landsteiner. 1868-1943". Obituary Notices of Fellows of the Royal Society. 5 (15): 294–324. doi:10.1098/rsbm.1947.0002.
  7. Jump up^ Ann Thwaite. "Marni Hodgkin obituary | Books". The Guardian. Retrieved 2016-03-11.

Further reading[edit]

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